GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL2 | increases expression | EXP | | 6480464 | CTD | Mitogens results in increased expression of IL2 mRNA | PMID:16055081 | IL2 | increases secretion | EXP | | 6480464 | CTD | Mitogens results in increased secretion of IL2 protein | PMID:16055081 | IL2 | multiple interactions | EXP | | 6480464 | CTD | Tacrolimus inhibits the reaction [Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]]; Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]; Zinc Sulfate inhibits the reaction [Mitogens results in increased secretion of IL2 protein] | PMID:16055081 | IL2 | increases expression | ISO | Il2 (Rattus norvegicus) | 6480464 | CTD | Mitogens results in increased expression of IL2 protein | PMID:19401694 | IL2 | increases expression | ISO | Il2 (Mus musculus) | 6480464 | CTD | Mitogens results in increased expression of IL2 protein | PMID:30664314 | IL2 | multiple interactions | ISO | Il2 (Rattus norvegicus) | 6480464 | CTD | Ciprofloxacin inhibits the reaction [irinotecan promotes the reaction [Mitogens results in increased expression of IL2 protein]]; irinotecan inhibits the reaction [Mitogens results in increased expression of IL2 protein]; irinotecan promotes the reaction [Mitogens results in increased expression of IL2 protein] | PMID:19401694 | | ||||||||||||||||||||||
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