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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620103
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bad
Name: BCL2-associated agonist of cell death
Acc ID: CHEBI:52289
Term: wortmannin
Definition: A delta-lactone that has formula C23H24O8.
Chemical ID: MESH:C009687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baddecreases phosphorylationEXP 6480464CTDwortmannin results in decreased phosphorylation of BAD proteinPMID:15190125
Badmultiple interactionsEXP 6480464CTDWortmannin inhibits the reaction [Mannitol results in increased phosphorylation of BAD protein]; Wortmannin inhibits the reaction [ursodoxicoltaurine results in increased phosphorylation of and affects the localization of BAD protein]PMID:15190125 PMID:15786717
Badmultiple interactionsISOBAD (Homo sapiens)6480464CTDwortmannin inhibits the reaction [Acrolein results in increased phosphorylation of BAD protein]; wortmannin inhibits the reaction [CXCL2 protein results in increased phosphorylation of BAD protein]PMID:15608143 PMID:19596284
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