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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67382
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Klkb1
Name: kallikrein B1
Acc ID: CHEBI:52261
Term: rose bengal
Definition: An organic potassium salt that is the dipotassium salt of 2,3,4,5-tetrachloro-6-(2,4,5,7-tetraiodo-6-hydroxy-3-oxoxanthen-9-yl)benzoic acid.
Chemical ID: MESH:D012395
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klkb1decreases response to substanceISORGD:108436480464CTDKLKB1 gene mutant form results in decreased susceptibility to Rose Bengal

PMID:25339356
Klkb1multiple interactionsISORGD:108436480464CTD7-Ala-angiotensin 1-7 inhibits the reaction [KLKB1 gene mutant form results in decreased susceptibility to Rose Bengal] nimesulide inhibits the reaction [KLKB1 gene mutant form results in decreased susceptibility to Rose Bengal] splitomicin inhibits the reaction [KLKB1 gene mutant form results in decreased susceptibility to Rose Bengal]

PMID:25339356
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