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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10996
Species: Mus musculus
RGD Object: Gene
Symbol: Nos2
Name: nitric oxide synthase 2, inducible
Acc ID: CHEBI:52221
Term: isothiocyanate
Definition: An organosulfur compound with the general formula R-N=C=S.
Chemical ID: MESH:D017879
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos2multiple interactionsEXP 6480464CTDIsothiocyanates inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Isothiocyanates inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]PMID:19159619
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