GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdkn1a | decreases expression | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | Furazolidone results in decreased expression of CDKN1A protein | PMID:26687534 | Cdkn1a | increases expression | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | Furazolidone results in increased expression of CDKN1A mRNA | PMID:26687534 | Cdkn1a | multiple interactions | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | CDKN1A mutant form inhibits the reaction [Furazolidone results in increased expression of HMOX1 protein]; CDKN1A mutant form inhibits the reaction [Furazolidone results in increased expression of NFE2L2 protein]; CDKN1A protein inhibits the reaction [Furazolidone results in increased activity of CASP3 protein]; CDKN1A protein inhibits the reaction [Furazolidone results in increased phosphorylation of PARP1 protein]; CDKN1A protein promotes the reaction [Furazolidone results in increased expression of HMOX1 protein]; CDKN1A protein promotes the reaction [Furazolidone results in increased expression of NFE2L2 protein]; Furazolidone promotes the reaction [Cycloheximide results in decreased expression of CDKN1A protein] | PMID:26687534 | | ||||||||||||||||||||||
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