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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732862
Species: Mus musculus
RGD Object: Gene
Symbol: Chek2
Name: checkpoint kinase 2
Acc ID: CHEBI:51913
Term: Goe 6976
Definition: An indolocarbazole that has formula C24H18N4O.
Chemical ID: MESH:C081021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chek2multiple interactionsISOCHEK2 (Homo sapiens)6480464CTDGo 6976 inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of CHEK2 protein]PMID:17320279
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