GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MAPK1 | decreases activity | EXP | | 6480464 | CTD | bufalin results in decreased activity of MAPK1 protein | PMID:21922632 | MAPK1 | increases phosphorylation | EXP | | 6480464 | CTD | bufalin results in increased phosphorylation of MAPK1 protein | PMID:10712238 | MAPK1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [bufalin results in increased phosphorylation of MAPK1 protein]; Ro 31-8220 inhibits the reaction [bufalin results in increased phosphorylation of MAPK1 protein]; SB 203580 promotes the reaction [bufalin results in increased phosphorylation of MAPK1 protein] | PMID:10712238 | |
Go Back to source page | Continue to Ontology report |