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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp4a1
Name: cytochrome P450, family 4, subfamily a, polypeptide 1
Acc ID: CHEBI:5141
Term: fomepizole
Definition: A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Chemical ID: MESH:C010238
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp4a1increases expressionEXP 6480464CTDfomepizole results in increased expression of CYP4A1 proteinPMID:20116195
Cyp4a1multiple interactionsEXP 6480464CTDfomepizole promotes the reaction [Ethanol results in increased expression of CYP4A1 protein]PMID:20116195
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