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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2933
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
Acc ID: CHEBI:5141
Term: fomepizole
Definition: A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Chemical ID: MESH:C010238
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itpr1multiple interactionsISORGD:7329786480464CTDfomepizole inhibits the reaction [Ethanol results in increased expression of and affects the localization of ITPR1 protein]

PMID:17241155
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.