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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628714
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd86
Name: CD86 molecule
Acc ID: CHEBI:51403
Term: 1,4-phenylenediamine
Definition: A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.
Chemical ID: MESH:C029728
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd86increases expressionISOCD86 (Homo sapiens)6480464CTD4-phenylenediamine results in increased expression of CD86 proteinPMID:12423654 PMID:19033392 PMID:19665512 PMID:20488241 PMID:24136171 PMID:32006680
Cd86multiple interactionsISOCD86 (Homo sapiens)6480464CTDbisindolylmaleimide I inhibits the reaction [4-phenylenediamine results in increased expression of CD86 protein]PMID:24136171
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