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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:51403
Term: 1,4-phenylenediamine
Definition: A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.
Chemical ID: MESH:C029728
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:107966480464CTD4-phenylenediamine results in increased expression of IL4 mRNA

PMID:11531941
increases secretionISORGD:107966480464CTD4-phenylenediamine results in increased secretion of IL4 protein

PMID:22245253
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.