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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553376
Species: Mus musculus
RGD Object: Gene
Symbol: Pycard
Name: PYD and CARD domain containing
Acc ID: CHEBI:51403
Term: 1,4-phenylenediamine
Definition: A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.
Chemical ID: MESH:C029728
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pycardincreases expressionISOPYCARD (Homo sapiens)6480464CTD4-phenylenediamine results in increased expression of PYCARD proteinPMID:31276767
Pycardmultiple interactionsISOPYCARD (Homo sapiens)6480464CTD4-phenylenediamine promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein]PMID:31276767
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