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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12260125
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CASP8
Name: caspase 8
Acc ID: CHEBI:51403
Term: 1,4-phenylenediamine
Definition: A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.
Chemical ID: MESH:C029728
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP8increases activityEXP 6480464CTD4-phenylenediamine results in increased activity of CASP8 protein

PMID:20156547
CASP8multiple interactionsEXP 6480464CTDbenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [4-phenylenediamine results in increased activity of CASP8 protein]

PMID:20156547
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