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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10717
Species: Mus musculus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:51403
Term: 1,4-phenylenediamine
Definition: A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.
Chemical ID: MESH:C029728
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1increases expressionEXP 6480464CTD4-phenylenediamine results in increased expression of HMOX1 mRNAPMID:23445166
Hmox1increases expressionISOHMOX1 (Homo sapiens)6480464CTD4-phenylenediamine results in increased expression of HMOX1 mRNAPMID:16314067 PMID:19033392 PMID:20491607 PMID:20713136 PMID:25724174 PMID:26244607 PMID:31967339
Hmox1multiple interactionsISOHMOX1 (Homo sapiens)6480464CTDBACH1 mRNA promotes the reaction [4-phenylenediamine results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA promotes the reaction [4-phenylenediamine results in increased expression of HMOX1 mRNA]PMID:26244607
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