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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A
Acc ID: CHEBI:51348
Term: tetraphene
Definition: An angular ortho-fused polycyclic arene consisting of four fused benzene rings.
Chemical ID: MESH:C030935
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1adecreases expressionISOCdkn1a (Mus musculus)6480464CTDbenz(a)anthracene results in decreased expression of CDKN1A mRNAPMID:26377693
Cdkn1aincreases expressionISOCDKN1A (Homo sapiens)6480464CTDbenz(a)anthracene results in increased expression of CDKN1A mRNAPMID:22236718
Cdkn1amultiple interactionsISOCdkn1a (Mus musculus)6480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CDKN1A mRNAPMID:27858113
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