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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2684
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ggt5
Name: gamma-glutamyltransferase 5
Acc ID: CHEBI:5134
Term: fluticasone
Definition: A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis.
Chemical ID: MESH:C065382
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ggt5increases activityISOGGT5 (Homo sapiens)6480464CTDFluticasone results in increased activity of GGT5 proteinPMID:11447392
Ggt5increases expressionISOGGT5 (Homo sapiens)6480464CTDFluticasone results in increased expression of GGT5 mRNAPMID:11447392
Ggt5multiple interactionsISOGGT5 (Homo sapiens)6480464CTD[Fluticasone results in increased activity of GGT5 protein] which results in increased metabolism of Leukotriene C4PMID:11447392
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