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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3403
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prl
Name: prolactin
Acc ID: CHEBI:51164
Term: lisuride
Definition: A monocarboxylic acid amide that has formula C20H26N4O.
Chemical ID: MESH:D008090
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prldecreases secretionEXP 6480464CTDLisuride analog results in decreased secretion of PRL protein; Lisuride results in decreased secretion of PRL proteinPMID:6492995
Prlmultiple interactionsISOPRL (Homo sapiens)6480464CTDLisuride inhibits the reaction [Metoclopramide results in increased secretion of PRL protein]; Lisuride results in decreased expression of and results in decreased secretion of PRL proteinPMID:386688
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