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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344001
Species: Homo sapiens
RGD Object: Gene
Symbol: GDF15
Name: growth differentiation factor 15
Acc ID: CHEBI:51052
Term: lucanthone
Definition: A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.
Chemical ID: MESH:D008154
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GDF15increases expressionEXP 6480464CTDLucanthone results in increased expression of GDF15 mRNAPMID:21148553
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