Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308450
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sgo2
Name: shugoshin 2
Acc ID: CHEBI:51052
Term: lucanthone
Definition: A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.
Chemical ID: MESH:D008154
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sgo2decreases expressionISOSGO2 (Homo sapiens)6480464CTDLucanthone results in decreased expression of SGO2 mRNAPMID:21148553
Go Back to source page   Continue to Ontology report