Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737448
Species: Mus musculus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:50866
Term: 3H-1,2-dithiole-3-thione
Definition: A 1,2-dithiole that has formula C3H2S3.
Chemical ID: MESH:C049325
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catincreases activityEXP 6480464CTD1,2-dithiol-3-thione results in increased activity of CAT proteinPMID:18367636
Catincreases expressionEXP 6480464CTD1,2-dithiol-3-thione results in increased expression of CAT mRNA; 1,2-dithiol-3-thione results in increased expression of CAT proteinPMID:18367636
Catmultiple interactionsEXP 6480464CTDNFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased activity of CAT protein]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of CAT mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of CAT protein]PMID:18367636
Go Back to source page   Continue to Ontology report