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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621176
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scd
Name: stearoyl-CoA desaturase
Acc ID: CHEBI:50859
Term: bexarotene
Definition: A retinoid that has formula C24H28O2.
Chemical ID: MESH:C095105
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scdincreases expressionEXP 6480464CTDbexarotene results in increased expression of SCD1 mRNAPMID:17630414 PMID:23292798
Scdmultiple interactionsEXP 6480464CTD[Tamoxifen co-treated with bexarotene] results in increased expression of SCD1 mRNAPMID:17630414
Scdincreases expressionISOSCD (Homo sapiens)6480464CTDBexarotene results in increased expression of SCD mRNAPMID:17178900 PMID:32123961
Scdincreases expressionISOScd1 (Mus musculus)6480464CTDbexarotene results in increased expression of SCD1 mRNAPMID:17178900
Scdmultiple interactionsISOSCD (Homo sapiens)6480464CTD[Bexarotene co-treated with GW 3965] results in increased expression of SCD mRNA; [Bexarotene co-treated with T0901317] results in increased expression of SCD mRNAPMID:32123961
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