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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731081
Species: Homo sapiens
RGD Object: Gene
Symbol: PGR
Name: progesterone receptor
Acc ID: CHEBI:50743
Term: cyproterone acetate
Definition: A chlorinated steroid that has formula C24H29ClO4.
Chemical ID: MESH:D017373
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to PGR protein modified form], Cyproterone Acetate binds to and results in increased activity of PGR protein

PMID:20599585, PMID:28751236
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.