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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cacna2d2
Name: calcium voltage-gated channel auxiliary subunit alpha2delta 2
Acc ID: CHEBI:50729
Term: mitoxantrone
Definition: A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Chemical ID: MESH:D008942
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7376096480464CTDMitoxantrone results in decreased expression of CACNA2D2 mRNA

PMID:26537877, PMID:28940058
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.