GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Parp1 | multiple interactions | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein; BCL2 protein inhibits the reaction [Mitoxantrone results in increased degradation of PARP1 protein]; BCL2L1 protein inhibits the reaction [Mitoxantrone results in increased degradation of PARP1 protein] | PMID:15582267 PMID:8840993 | |
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