GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp8 | decreases expression | ISO | Casp8 (Rattus norvegicus) | 6480464 | CTD | Minocycline results in decreased expression of CASP8 mRNA | PMID:14998631 | Casp8 | multiple interactions | ISO | Casp8 (Rattus norvegicus) | 6480464 | CTD | Minocycline inhibits the reaction [HTT protein mutant form results in increased activity of CASP8 protein]; Minocycline results in decreased expression of and results in decreased activity of CASP8 protein | PMID:12930891 PMID:14998631 | |
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