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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3254
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Reg3b
Name: regenerating family member 3 beta
Acc ID: CHEBI:50693
Term: milrinone
Definition: A member of the class of bipyridines that is 2-pyridone which is substituted at positions 3, 5, and 6 by cyano, pyrid-4-yl, and methyl groups, respectively. It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure.
Chemical ID: MESH:D020105
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Reg3bincreases expressionEXP 6480464CTDMilrinone results in increased expression of REG3B mRNAPMID:22936366
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