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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708392
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a9
Name: cytochrome P450, family 3, subfamily a, polypeptide 9
Acc ID: CHEBI:50692
Term: mifepristone
Definition: A 3-oxo steroid that has formula 429.59374.
Chemical ID: MESH:D015735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a9multiple interactionsISOCYP3A5 (Homo sapiens)6480464CTDMifepristone inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Mifepristone inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of CYP3A5 mRNA]PMID:12538830
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