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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3403
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prl
Name: prolactin
Acc ID: CHEBI:50692
Term: mifepristone
Definition: A 3-oxo steroid that has formula 429.59374.
Chemical ID: MESH:D015735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prlincreases expressionEXP 6480464CTDMifepristone results in increased expression of PRL mRNA; Mifepristone results in increased expression of PRL proteinPMID:18832805
Prlmultiple interactionsEXP 6480464CTDMifepristone promotes the reaction [estradiol 3-benzoate results in increased secretion of PRL protein]PMID:2159045
Prlincreases expressionISOPRL (Homo sapiens)6480464CTDMifepristone results in increased expression of PRL mRNAPMID:17584828
Prlmultiple interactionsISOPRL (Homo sapiens)6480464CTDMifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of PRL mRNA]PMID:15774544
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