GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TLR4 | increases expression | ISO | Tlr4 (Rattus norvegicus) | 6480464 | CTD | Methimazole results in increased expression of TLR4 mRNA | PMID:30047161 | TLR4 | multiple interactions | ISO | Tlr4 (Rattus norvegicus) | 6480464 | CTD | [Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein; gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein] | PMID:26177832 | | ||||||||||||||||||||||
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