Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349204
Species: Homo sapiens
RGD Object: Gene
Symbol: CHRDL1
Name: chordin like 1
Acc ID: CHEBI:50667
Term: mercaptopurine
Definition: A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.
Chemical ID: MESH:D015122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CHRDL1decreases expressionISOChrdl1 (Rattus norvegicus)6480464CTDMercaptopurine results in decreased expression of CHRDL1 mRNAPMID:23358152
Go Back to source page   Continue to Ontology report