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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1603716
Species: Homo sapiens
RGD Object: Gene
Symbol: CCR2
Name: C-C motif chemokine receptor 2
Acc ID: CHEBI:50648
Term: 9-cis-retinoic acid
Definition: A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.
Chemical ID: MESH:C103303
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCR2decreases expressionEXP 6480464CTDAlitretinoin results in decreased expression of CCR2 mRNA; Alitretinoin results in decreased expression of CCR2 proteinPMID:16712875
CCR2multiple interactionsEXP 6480464CTD4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Alitretinoin results in decreased expression of CCR2 mRNA]PMID:16712875
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