GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | [Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Alitretinoin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] | PMID:15968640 PMID:16303184 | Tnf | decreases expression | ISO | TNF (Homo sapiens) | 6480464 | CTD | Alitretinoin results in decreased expression of TNF mRNA; Alitretinoin results in decreased expression of TNF protein | PMID:17118196 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Alitretinoin inhibits the reaction [TNF protein results in increased expression of CYP4F11 mRNA]; Alitretinoin inhibits the reaction [TNF protein results in increased phosphorylation of JUN protein] | PMID:19812349 | | ||||||||||||||||||||||
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