GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | decreases activity | EXP | | 6480464 | CTD | fipronil results in decreased activity of CAT protein | PMID:25721553 | Cat | decreases expression | EXP | | 6480464 | CTD | fipronil results in decreased expression of CAT mRNA | PMID:25721553 | Cat | multiple interactions | EXP | | 6480464 | CTD | Ascorbic Acid inhibits the reaction [fipronil results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [fipronil results in decreased activity of CAT protein] | PMID:25721553 | Cat | affects binding | ISO | CAT (Homo sapiens) | 6480464 | CTD | fipronil binds to CAT protein | PMID:32278787 | Cat | decreases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | fipronil results in decreased activity of CAT protein | PMID:30777931 PMID:32651782 | Cat | decreases expression | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | fipronil results in decreased expression of CAT protein | PMID:36113622 | Cat | increases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | fipronil results in increased activity of CAT protein | PMID:36916050 | Cat | multiple interactions | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Allopurinol inhibits the reaction [fipronil results in increased activity of CAT protein]; Plant Extracts inhibits the reaction [fipronil results in decreased activity of CAT protein] | PMID:30777931 PMID:32651782 PMID:36916050 | | ||||||||||||||||||||||
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