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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61861
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabra6
Name: gamma-aminobutyric acid type A receptor subunit alpha6
Acc ID: CHEBI:5063
Term: fipronil
Definition: A racemate comprising equimolar amounts of (R)- and (S)-fipronil.
Chemical ID: MESH:C082360
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabra6multiple interactionsISOGABRA6 (Homo sapiens)6480464CTDfipronil results in decreased activity of [GABRA6 protein binds to GABRB1 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]PMID:29038840
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