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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552388
Species: Mus musculus
RGD Object: Gene
Symbol: Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Acc ID: CHEBI:5063
Term: fipronil
Definition: A racemate comprising equimolar amounts of (R)- and (S)-fipronil.
Chemical ID: MESH:C082360
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acacaincreases expressionEXP 6480464CTDfipronil results in increased expression of ACACA mRNAPMID:27103584
Acacamultiple interactionsEXP 6480464CTDAICA ribonucleotide inhibits the reaction [fipronil results in increased expression of and results in decreased phosphorylation of ACACA protein]; fipronil results in increased expression of and results in decreased phosphorylation of ACACA proteinPMID:27103584
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