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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734088
Species: Homo sapiens
RGD Object: Gene
Symbol: PSMD1
Name: proteasome 26S subunit, non-ATPase 1
Acc ID: CHEBI:5062
Term: finasteride
Definition: An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.
Chemical ID: MESH:D018120
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PSMD1increases expressionISOPsmd1 (Rattus norvegicus)6480464CTDFinasteride results in increased expression of PSMD1 mRNA; Finasteride results in increased expression of PSMD1 proteinPMID:24136188 PMID:27750143
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