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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:50594
Term: carbon nanotube
Definition: A molecule consisting of a graphene cylinder or two or more concentric graphene cylinders.
Chemical ID: MESH:D037742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTDNanotubes, Carbon results in increased expression of BAX proteinPMID:22020378
Baxmultiple interactionsEXP 6480464CTDVitamin E inhibits the reaction [Nanotubes, Carbon results in increased expression of BAX protein]PMID:22020378
Baxincreases expressionISOBax (Mus musculus)6480464CTDNanotubes, Carbon analog results in increased expression of BAX mRNA; Nanotubes, Carbon results in increased expression of BAX mRNA; Nanotubes, Carbon results in increased expression of BAX proteinPMID:24929217 PMID:25554681
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDNanotubes, Carbon results in increased expression of BAX mRNA; Nanotubes, Carbon results in increased expression of BAX proteinPMID:15585362 PMID:32493873
Baxmultiple interactionsISOBax (Mus musculus)6480464CTDNanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of BAX protein]PMID:32068018
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