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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10256
Species: Mus musculus
RGD Object: Gene
Symbol: C3
Name: complement component 3
Acc ID: CHEBI:50594
Term: carbon nanotube
Definition: A molecule consisting of a graphene cylinder or two or more concentric graphene cylinders.
Chemical ID: MESH:D037742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C3affects expressionEXP 6480464CTDNanotubes, Carbon affects the expression of C3 mRNAPMID:23845593 PMID:25554681
C3increases expressionEXP 6480464CTDNanotubes, Carbon analog results in increased expression of C3 mRNA; Nanotubes, Carbon results in increased expression of C3; Nanotubes, Carbon results in increased expression of C3 mRNAPMID:21654424 PMID:25554681 PMID:25620056
C3increases secretionEXP 6480464CTDNanotubes, Carbon results in increased secretion of C3 proteinPMID:25598225
C3multiple interactionsEXP 6480464CTD[Nanotubes, Carbon co-treated with Aluminum Oxide] results in increased secretion of C3 proteinPMID:25598225
C3decreases expressionISOC3 (Homo sapiens)6480464CTDNanotubes, Carbon results in decreased expression of C3 mRNAPMID:23634900
C3increases expressionISOC3 (Rattus norvegicus)6480464CTDNanotubes, Carbon results in increased expression of C3 mRNAPMID:24911292
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