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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731007
Species: Mus musculus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:50462
Term: citronellol
Definition: A monoterpenoid that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7.
Chemical ID: MESH:C007078
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2multiple interactionsEXP 6480464CTDcitronellol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; citronellol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]PMID:20506077
Ptgs2multiple interactionsISOPtgs2 (Rattus norvegicus)6480464CTDcitronellol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 protein]PMID:31926054
Ptgs2multiple interactionsISOPTGS2 (Homo sapiens)6480464CTDcitronellol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; citronellol inhibits the reaction [PPARG protein results in increased expression of PTGS2 mRNA]PMID:21597168
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