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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:50399
Term: 3',4',7-trihydroxyisoflavone
Definition: A 7-hydroxyisoflavone that is daidzein substituted by a hydroxy group at position 3'.
Chemical ID: MESH:C061213
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionISOBAX (Homo sapiens)6480464CTD3',4',7-trihydroxyisoflavone results in increased expression of BAX mRNAPMID:22914566
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of BAX mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of BAX mRNA]PMID:22914566
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