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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736024
Species: Mus musculus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:50385
Term: hemin
Definition: It is used as a prescription medication to relieve repeated attacks of acute intermittent porphyria related to the menstrual cycle in affected women.
Chemical ID: MESH:D006427
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9decreases expressionISOMapk9 (Rattus norvegicus)6480464CTDHemin results in decreased expression of MAPK9 mRNAPMID:20016031
Mapk9multiple interactionsISOMapk9 (Rattus norvegicus)6480464CTDchromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA]]; Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA]PMID:19190261
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