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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620020
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptger2
Name: prostaglandin E receptor 2
Acc ID: CHEBI:50385
Term: hemin
Definition: It is used as a prescription medication to relieve repeated attacks of acute intermittent porphyria related to the menstrual cycle in affected women.
Chemical ID: MESH:D006427
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptger2increases response to substanceISOPtger2 (Mus musculus)6480464CTDPTGER2 gene mutant form results in increased susceptibility to HeminPMID:25451967
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