GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | multiple interactions | EXP | | 6480464 | CTD | [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with Hemin] results in increased cleavage of CASP3 protein; Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased cleavage of CASP3 protein]; Hemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased cleavage of CASP3 protein]; Hemin inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Hemin inhibits the reaction [Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein]; Hemin inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; Hemin inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [Hemin inhibits the reaction [Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein]] | PMID:17173083 PMID:18845130 PMID:19150641 PMID:19520142 PMID:26747958 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Hemin results in increased cleavage of CASP3 protein | PMID:27815112 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | [SESN2 protein affects the susceptibility to Hemin] which results in decreased expression of CASP3 protein modified form | PMID:31054940 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Hemin promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein] | PMID:27815112 | | ||||||||||||||||||||||
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