GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcl15 | increases expression | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | cadmium sulfate results in increased expression of CXCL8 mRNA; cadmium sulfate results in increased expression of CXCL8 protein | PMID:21783983 PMID:22094458 PMID:22142850 | Cxcl15 | increases secretion | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | cadmium sulfate results in increased secretion of CXCL8 protein | PMID:22094458 PMID:22142850 | Cxcl15 | multiple interactions | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; Cycloheximide inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; MAPK1 mutant form inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; MAPK3 mutant form inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; SB 203580 inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; U 0126 inhibits the reaction [cadmium sulfate results in increased expression of CXCL8 mRNA]; U 0126 inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein] | PMID:22094458 PMID:22142850 | | ||||||||||||||||||||||
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