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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2544
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Egr1
Name: early growth response 1
Acc ID: CHEBI:50225
Term: razoxane
Definition: A N-alkylpiperazine that has formula C11H16N4O4.
Chemical ID: MESH:D011929
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egr1decreases expressionISOEgr1 (Mus musculus)6480464CTDRazoxane results in decreased expression of EGR1 proteinPMID:12714334
Egr1multiple interactionsISOEgr1 (Mus musculus)6480464CTD[Doxorubicin co-treated with Razoxane] results in decreased expression of EGR1 proteinPMID:12714334
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