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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307072
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ndufb4
Name: NADH:ubiquinone oxidoreductase subunit B4
Acc ID: CHEBI:50223
Term: (+)-dexrazoxane
Definition: A razoxane that has formula C11H16N4O4.
Chemical ID: MESH:D064730
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ndufb4increases expressionISONdufb4 (Mus musculus)6480464CTDDexrazoxane results in increased expression of NDUFB4 mRNAPMID:26873546
Ndufb4multiple interactionsISONdufb4 (Mus musculus)6480464CTD[Doxorubicin co-treated with Dexrazoxane] results in increased expression of NDUFB4 mRNAPMID:26873546
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