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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3310
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pfkfb4
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Acc ID: CHEBI:50161
Term: motexafin gadolinium
Definition: A metallotexaphyrin that has formula C52H72GdN5O14.
Chemical ID: MESH:C437683
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pfkfb4increases expressionISOPFKFB4 (Homo sapiens)6480464CTDmotexafin gadolinium results in increased expression of PFKFB4 mRNAPMID:16357179
Pfkfb4multiple interactionsISOPFKFB4 (Homo sapiens)6480464CTD[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB4 mRNAPMID:16357179
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