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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Maoa
Name: monoamine oxidase A
Acc ID: CHEBI:50157
Term: (5-hydroxyindol-3-yl)acetaldehyde
Definition: An aldehyde that is acetaldehyde substituted by a 5-hydroxyindol-3-yl group.
Chemical ID: MESH:C004277
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Maoaincreases abundanceISORGD:621916480464CTDMAOA protein results in increased abundance of hydroxyindoleacetaldehyde

PMID:23009399
Maoamultiple interactionsISORGD:621916480464CTD[MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde Luteolin inhibits the reaction [[MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde] Luteolin inhibits the reaction [MAOA protein results in increased abundance of hydroxyindoleacetaldehyde] Quercetin inhibits the reaction [[MAOA protein results in increased metabolism of Serotonin] which results in increased abundance of hydroxyindoleacetaldehyde] Quercetin inhibits the reaction [MAOA protein results in increased abundance of hydroxyindoleacetaldehyde]

PMID:23009399
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