GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PDGFB | multiple interactions | EXP | | 6480464 | CTD | Decitabine results in decreased activity of [PDGFB protein binds to PDGFB protein] | PMID:23423710 | PDGFB | multiple interactions | ISO | Pdgfb (Rattus norvegicus) | 6480464 | CTD | Decitabine inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of H19 mRNA]; Decitabine inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ACTA2 protein]; Decitabine inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of COL1A1 protein]; Decitabine inhibits the reaction [PDGFB protein results in decreased expression of RASAL1 mRNA]; Decitabine inhibits the reaction [PDGFB protein results in decreased expression of RASAL1 protein]; Decitabine inhibits the reaction [PDGFB protein results in increased expression of MECP2 mRNA]; Decitabine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Decitabine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] | PMID:22056649 PMID:30010033 | | ||||||||||||||||||||||
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