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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736378
Species: Homo sapiens
RGD Object: Gene
Symbol: APOE
Name: apolipoprotein E
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
APOEmultiple interactionsISOApoe (Rattus norvegicus)6480464CTDDecitabine inhibits the reaction [Cadmium Chloride results in decreased expression of APOE mRNA]; Decitabine inhibits the reaction [Cadmium results in decreased expression of APOE mRNA]; GW 3965 promotes the reaction [Decitabine inhibits the reaction [Cadmium Chloride results in decreased expression of APOE mRNA]]PMID:28315714 PMID:30185694
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